A single dose after reconstitution is 0.5 mL. Ann Intern Med. Symptoms of a severe allergic reaction can include hives, swelling of the face and throat, difficulty breathing, a fast heartbeat, dizziness, and weakness. Saving Lives, Protecting People, Shingles vaccination is the only way to protect against, National Center for Immunization and Respiratory Diseases, U.S. Department of Health & Human Services. Mills R, Tyring SK, Levin MJ, Parrino J, Li X, et al. Prevention of herpes zoster: Recommendations of the Advisory Committee on Immunization Practices (ACIP). Shingles, or herpes zoster, is a painful skin rash that develops on one side of the face or body. problems with balance or eye movement; or. You can review and change the way we collect information below. Some vaccines against COVID-19 also use nucleic acids. 2-Phenoxyethanol is a glycol ether used as a preservative in vaccines. An allergic reaction could occur after the vaccinated person leaves the clinic. Your reaction to each dose may be different; just because you have a reaction to the first dose does not mean that you will have a reaction to the second. aluminum hydroxide, sodium chloride, phosphate buffers [disodium phosphate dihydrate, sodium dihydrogen phosphate dihydrate], Hepatitis B Vaccine (Recombinant), Adjuvanted, Manufacturer: Dynavax Technologies Corporation, Hansenula polymorpha yeast, fermentation media [vitamins, mineral salts], CpG 1018 adjuvant [22-mer phosphorothioate linked oligodeoxynucleotide, phosphate buffered saline (sodium chloride, sodium phosphate, dibasic dodecahydrate, monobasic dihydrate, polysorbate 80)], yeast protein, yeast DNA, deoxycholate, CpG 1018, Human Papillomavirus Quadrivalent (Types 6, 11, 16, 18) Vaccine, Recombinant, Saccharomyces cerevisiae, fermentation media [vitamins, amino acids, mineral salts, carbohydrates], amorphous aluminum hydroxyphosphate sulfate, amorphous aluminum hydroxyphosphate sulfate adjuvant, sodium chloride, L-histidine, polysorbate 80, sodium borate, yeast protein, water, Human Papillomavirus 9-valent Vaccine, Recombinant, amorphous aluminum hydroxyphosphate sulfate, sodium chloride, L-histidine, polysorbate 80, sodium borate, yeast protein, water, Human Papillomavirus Bivalent (Types 16, 18) Vaccine, Recombinant, serum-free culture media [lipids, vitamins, amino acids, mineral salts], hydroxide salt, AS04 [3-O-desacyl-4-monophosphoryl lipid A (MPL), hydroxide salt, sodium chloride, sodium dihydrogen phosphate dihydrate, water, 3-O-desacyl-4-monophosphoryl lipid A (MPL), aluminum hydroxide, sodium chloride, sodium dihydrogen phosphate dihydrate, insect cell and viral protein, bacterial cell protein, 19. Shingrix Ingredients . Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. Hum Vaccin. Many people have redness and swelling on their arm spanning several inches where they got the shot. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. Vaccine. Chicago, Illinois 60654 USA, Natalie Leppard Basic information about the shingles vaccine, Vaccine recommendations and contraindications; composition, dosage, administration, and co-administration with other vaccines; Shingrix FAQ; storage and handling. DTaP Vaccine(diphtheria, tetanus, & pertussis), Diphtheria & Tetanus Toxoids & Acellular Pertussis Vaccine Adsorbed, Manufacturer: GlaxoSmithKline Biologicals, Fenton medium (containing bovine extract), Latham medium, Stainer-Scholte liquid medium, glutaraldehyde, formaldehyde, aluminum hydroxide. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. 2021), Afluria Quadrivalent Southern Hemisphere Package Insert (2021), Afluria Quadrivalent: allantoic fluid of embryonated chicken eggs, sucrose density gradient, beta-propiolactone, sodium taurodeoxycholate, phosphate buffered isotonic solution. People sometimes faint after medical procedures, including vaccination. Saccharomyces cerevisiae cells, aluminum hydroxide, listyeast protein. 14, 2016), Mueller Hinton casein agar, Watson Scherp casamino acid media, water, thimerosal, polysaccharide from each of serogroups A, C, Y, and W-135, lactose, Meningococcal (Groups A, C, Y, W) Conjugate Vaccine, Mueller Hinton agar medium, Watson Scherp medium, carbonyldiimidazole (CDI), adipic acid dihydrazide (ADH), periodate, ammonium sulfate, formaldehyde, sodium chloride, sodium acetate, formaldehyde, Pneumococcal 13-valent Conjugate Vaccine (Diphtheria CRM197 Protein), soy peptone broth, casamino acids and yeast extract-based medium, chemically-defined medium, ammonium sulfate, polysorbate 80, succinate buffer, aluminum phosphate. People who have had shingles in the past and people who have received varicella (chickenpox) vaccine are recommended to get recombinant shingles vaccine. . You will be subject to the destination website's privacy policy when you follow the link. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. World Health Organization, Production and Control of Tetanus Vaccine: A Training Curriculum, Module III: Principles of Tetanus Vaccine Production, who.int, Sep. 3, 1999, ProCon/Encyclopaedia Britannica, Inc. Zostavax will no longer be sold in the United States starting July 1, 2020. They help us to know which pages are the most and least popular and see how visitors move around the site. These same fetal cells obtained from the early 1960s have continued to grow in the laboratory and are used to make . Viruses can be grown in chicken eggs before being used in vaccinations. DTaP-IPV-Hib-HepB (diphtheria, tetanus, pertussis, polio, haemophilus influenzae type B, & hepatitis B), 12. About 1 out of 6 people had symptoms severe enough to prevent them from doing regular activities. Last modified on November 28, 2022. Questions about Herpes Zoster and Zostavax. For other signs that concern you, call your health care provider. Safety of Zoster Vaccine in Elderly Adults Following Documented Herpes Zoster. Limitations of Use: For some people, the pain can last for months or even years after the rash goes away. An older adult with shingles is more likely to develop PHN and have longer lasting and more severe pain than a younger person. She . MMR & Varicella (measles, mumps, rubella, & chickenpox), 33. Healy, S. Teleki, A.V. The two-dose vaccine is more than 90% effective at preventing shingles, the CDC reports. You should tell patients to expect such reactions as pain, swelling, and redness . If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. Two doses of Shingrix provides more than 90% protection against shingles and postherpetic neuralgia (PHN), the most common complication of shingles. 2021), sodium chloride, monobasic sodium phosphate, dibasic sodium phosphate, and polysorbate 20 (Tween20), baculovirus and Spodoptera frugiperda cell proteins, baculovirus and cellular DNA, Triton X-100, Influenza Vaccine,Live, Intranasal (Quadrivalent, Types A and Types B), FluMist Quadrivalent Package Insert (Aug. 2021), specific pathogen-free (SPF) eggs, stabilizing buffer, monosodium glutamate, hydrolyzed porcine gelatin, arginine, sucrose, dibasic potassium phosphate, monobasic potassium phosphate, ovalbumin, gentamicin sulfate, ethylenediaminetetraacetic acid (EDTA), Influenza Virus Vaccine (Quadrivalent, Types A and Types B), Manufacturer: Glaxosmithkline Biologicals, Fluarix Quadrivalent Package Insert (2021), octoxynol-10 (TRITON X-100), tocopheryl hydrogen succinate, polysorbate 80 (Tween 80), hydrocortisone, gentamicin sulfate, ovalbumin, formaldehyde, sodium deoxycholate, Fluzone High-Dose Quadrivalent Package Insert (July 2021), Fluzone Quadrivalent Package Insert (2021), Fluzone Intradermal Quadrivalent Package Insert (May 10, 2016), Fluzone Quadrivalent Southern Hemisphere Package Insert (2021), Fluzone High-Dose Quadrivalent: embryonated chicken eggs, formaldehyde, linear sucrose density gradient solution, octylphenol ethoxylate (Triton X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone Quadrivalent: embryonated chicken eggs, formaldehyde, linear sucrose density gradient solution , octylphenol ethoxylate (Triton X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone Intradermal Quadrivalent: embryonated chicken eggs, formaldehyde, linear sucrose density gradient solution, octylphenol ethoxylate (Triton 17 X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone Quadrivalent Southern Hemisphere: embryonated chicken eggs, formaldehyde, linear sucrose density gradient solution, octylphenol ethoxylate (Triton X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone High-Dose Quadrivalent: sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, gelatin, Fluzone Quadrivalent: thimerosal, sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, Fluzone Intradermal Quadrivalent: sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, Fluzone Quadrivalent Southern Hemisphere: thimerosal, sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, Flulaval Quadrivalent Package Insert (2021), phosphate-buffered saline solution, ovalbumin, formaldehyde, sodium deoxycholate, -tocopheryl hydrogen succinate, polysorbate 80, Japanese Encephalitis Virus Vaccine, Inactivated, Adsorbed, Vero cells, protamine sulfate, sucrose density gradient, formaldehyde, aluminum hydroxide, formaldehyde, bovine serum albumin, host cell DNA, sodium metabisulphite, host cell protein, protamine sulfate, 23. We take your privacy seriously. . There is currently . A 2013 study showed that patients with a history of a previous shingles rash had the same side effects after Zostavax as those with no history of shingles. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. Local and systemic grade 3 reactions among immunocompromised adults were evaluated in six studies in five immunocompromised groups. Bovine serum comes from blood taken from domestic cattle. Harpaz R, Ortega-Sanchez IR, Seward JF. You can submit a report of your side effects to the Vaccine Adverse Event Reporting System through the website (. 2021), ProQuad Refrigerated Package Insert (Oct. 2018), Refrigerator-Stable Formulation: chick embryo cell culture, WI-38 human diploid lung fibroblasts, MRC-5 cells, Frozen Formulation Recombinant Human Albumin (RHA): embryo cell culture; WI-38 human diploid lung fibroblasts, MRC-5 cells, Frozen Formulation Human SerumAlbumin (HSA): chick embryo cell culture, WI-38 human diploid lung fibroblasts, MRC-5 cells, Frozen: chick embryo cell culture, WI-38 human diploid lung, MRC-5 cells, Refrigerated: chick embryo cell culture, WI-38 human diploid lung fibroblasts, MRC-5 cells, Refrigerator-Stable Formulation: sucrose, hydrolyzed gelatin, urea, sodium chloride, sorbitol, monosodium L-glutamate, sodium phosphate, recombinant human albumin, sodium bicarbonate, potassium phosphate, potassium chloride, residual components of MRC-5 cells including DNA and protein, neomycin, bovine serum albumin, other buffer and media ingredients, Frozen Formulation Recombinant Human Albumin (RHA): sucrose, hydrolyzed gelatin, sodium chloride, sorbitol, monosodium L-glutamate, sodium phosphate dibasic, recombinant human albumin, sodium bicarbonate, potassium phosphate monobasic, potassium chloride; potassium phosphate dibasic, residual components of MRC-5 cells including DNA and protein, neomycin, bovine calf serum, other buffer and media ingredients, Frozen Formulation Human SerumAlbumin (HSA): sucrose, hydrolyzed gelatin, urea, sodium chloride, sorbitol, monosodium L-glutamate, sodium phosphate, recombinant human albumin, sodium bicarbonate, potassium phosphate, potassium chloride, residual components of MRC-5 cells including DNA and protein, neomycin, bovine serum albumin, other buffer and media ingredients, Frozen: sucrose, hydrolyzed gelatin, sodium chloride, sorbitol, monosodium L-glutamate, sodium phosphate dibasic, recombinant human albumin, sodium bicarbonate, potassium phosphate monobasic, potassium chloride, potassium phosphate dibasic, residual components from the manufacturing process [MRC-5 cells including DNA and protein, neomycin, bovine calf serum, other buffer and media ingredients], Refrigerated: sucrose, sorbitol, hydrolyzed gelatin, urea, sodium chloride, sodium phosphate, monosodium L-glutamate, recombinant human albumin, sodium bicarbonate, potassium phosphate, potassium chloride, residual components from the manufacturing process [MRC-5 cells including DNA and protein, neomycin, bovine calf serum, other buffer and media ingredients], Meningococcal (Groups A, C, Y, and W-135) Oligosaccharide Diphtheria CRM197 Conjugate Vaccine, Manufacturer: GlaxoSmithKline Biologicals SA, Franz Complete medium, formaldehyde, CY medium [yeast extracts, amino acids], Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine, Mueller Hinton agar, Watson Scherp media [casamino acid], modified culture medium [hydrolyzed casein], formaldehyde, ammonium sulfate, sodium phosphate buffered isotonic sodium chloride solution, formaldehyde, Manufacturer: Novartis Vaccines and Diagnostics, Inc, Escherichia coli, deoxycholate, aluminum hydroxide, Neisserial adhesin A (NadA), Neisserial Heparin Binding Antigen (NHBA), factor H binding protein (fHbp), outer membrane vesicles (OMV), aluminum hydroxide, sodium chloride, histidine, sucrose, kanamycin. Cookies used to make website functionality more relevant to you. Your health care provider can give you more information. Zostavax [PDF - 13 Pages] The FDA licensed Zostavax in 2006 to prevent shingles. Some vaccines, like influenza (flu) vaccines, are modified frequently and you may wish to consult your doctors office or pharmacy for the most current information. Recombinant zoster (shingles) vaccine can prevent shingles. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. The CDC recommends that adults get a Tdap (tetanus, diphtheria, and pertussis) or Td (tetanus, diphtheria) booster shot every 10 years. Safety, tolerability, and immunogenicity after 1 and 2 doses of zoster vaccine in healthy adults 60 years of age. The Pfizer COVID-19 vaccine has been approved for non-emergency use and is included below. Shingrix provides stronger protection against shingles compared to Zostavax. CDC recommends that adults 50 years and older get two doses of the shingles vaccine called Shingrix (recombinant zoster vaccine) to prevent shingles and the complications from the disease. Most side effects are mild to moderate, and last 1-3 days. DTaP-IPV-Hib Vaccine(diphtheria, tetanus, pertussis, polio, & haemophilus influenzae type B), Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Inactivated Poliovirus and Haemophilus b Conjugate (Tetanus Toxoid Conjugate) Vaccine, Pentacel version 1 Package Insert (Feb. 2021), Pentacel version 2 Package Insert (Dec. 2019), version 1: Muellers growth medium, ammonium sulfate, formaldehyde, Mueller-Miller casamino acid medium without beef heart infusion, aluminum phosphate, Stainer-Scholte medium, casamino acids, dimethyl-betacyclodextrin, glutaraldehyde, aluminum phosphate, MRC-5 cells,, CMRL (Connaught Medical Research Laboratories) 1969 medium (supplemented with calf serum), Medium 199 (without calf serum), 2-phenoxyethanol, water, semi-synthetic medium, version 2: Muellers growth medium, ammonium sulfate, formaldehyde, Mueller-Miller casamino acid medium without beef heart infusion, aluminum phosphate, Stainer-Scholte medium, casamino acids, dimethyl-beta310 cyclodextrin, glutaraldehyde, Vero cells, Iscoves medium (supplemented with calf serum), M199 medium without calf serum, 2-phenoxyethanol, water, version 1: filamentous hemagglutinin (FHA), pertactin (PRN), fimbriae types 2 and 3 (FIM), aluminum phosphate, polysorbate 80, sucrose, formaldehyde, glutaraldehyde, bovine serum albumin, 2-phenoxyethanol, neomycin, polymyxin B sulfate. Shingles cannot be passed from one person to another, but the virus that causes shingles can spread and cause chickenpox in someone who has never had chickenpox or has never received chickenpox vaccine. Child and Adult Immunization Schedules To receive email updates about this page, enter your email address: We take your privacy seriously. Reporting is encouraged for any clinically significant adverse event even if it is uncertain whether the vaccine caused the event. Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. ProCon.org. Safety of zoster vaccine in adults from a large managed-care cohort: A Vaccine Safety Datalink study. Other effects include: Many people who get the vaccine have muscle aches, headaches, or feel tired. You may get the Shingrix vaccine even if you've already had shingles. Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. Hep A & Hep B (hepatitis A & hepatitis B), 24. Also, you are more likely to have severe, long-term pain if you get shingles when you are older. Relevant information, including the package insert if the FDA has uploaded it after this note, is available here: https://www.fda.gov/vaccines-blood-biologics/vaccines/fluad], Afluria Quadrivalent Package Insert (Mar. This vaccine is safe and may be used until the supply expires (before or by November 2020). filamentous hemagglutinin (FHA), pertactin (69 kiloDalton outer membrane protein), aluminum hydroxide, sodium chloride, formaldehyde, polysorbate 80 (Tween 80). Anyone who has had chickenpox in the past can get shingles because VZV remains in the body after a person recovers from chickenpox. You can review and change the way we collect information below. You should get the shingles vaccine even if you: CDC twenty four seven. Remember that the pain from shingles can last a lifetime, and these side effects should only last a few days. See the Recommendations of the Advisory Committee on Immunization Practices (ACIP) for Shingrix (2018). Antivirals that can treat shingles include: acyclovir valacyclovir famciclovir Additionally, there are many home remedies people can try to help alleviate discomfort. These cookies may also be used for advertising purposes by these third parties. Centers for Disease Control and Prevention. Manufacturer: Emergent Travel Health, Inc. Vaxchora Frozen Package Insert (June 2016)Vachora Package Insert (Dec. 2020), frozen: casamino acids, yeast extract, mineral salts, anti-foaming agent, ascorbic acid, Hy-Case SF, sodium chloride, sucrose, dried lactose, other: casamino acids, yeast extract, mineral salts, anti-foaming agent, ascorbic acid, Hy-Case SF, sucrose, anhydrous lactose, frozen: sodium bicarbonate, sodium carbonate, ascorbic acid, dried lactose, sucrose, sodium chloride, Hy-Case SF, other: sodium bicarbonate, sodium carbonate, ascorbic acid, anhydrous lactose, sucrose, Hy-Case SF, anhydrous lactose, Manufacturer: BioNTech Manufacturing GmbH, [Editors Note: This vaccine is commonly known as the Pfizer coronavirus vaccine. These side effects may temporarily prevent a vaccinated person from doing regular activities. By preventing shingles, recombinant shingles vaccine also protects against PHN and other complications. 2010 Jun 7;28(25):4204-9. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. All information these cookies collect is aggregated and therefore anonymous. CDC uses 3 systems to monitor vaccine safety: English D. Willis, Meredith Woodward, Elizabeth Brown, Zoran Popmihajlov, Patricia Saddier, Paula W. Annunziato, Neal A. Halsey, Anne A. Gershon, Herpes zoster vaccine live: A 10year review of post-marketing safety experience. ], [Editors Note: The MLA citation style requires double spacing within entries. The risk of PHN increases with age. The Vaccine Adverse Event Reporting System (VAERS) is an early warning system, co-managed by CDC and FDA, that monitors for potential vaccine safety problems. Cohen J. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. Thank you for taking the time to confirm your preferences. There are currently two shingles vaccines licensed and available for use in the United States: Shingrix (recombinant zoster vaccine) and Zostavax (zoster vaccine live). Safety of Zoster Vaccine in Elderly Adults Following Documented Herpes Zoster. Cookies used to make website functionality more relevant to you. DTaP (diphtheria, tetanus, & pertussis), 9. But it was used in the United States from 2006 to November 2020. Both vials of Shingrix must be refrigerated at a temperature of 36-46 F. Do not use if exposed to temperatures below 36 F. Prepare Shingrix by reconstituting the antigen component with the adjuvant suspension component. This long-lasting pain is called postherpetic neuralgia (PHN), and it is the most common complication of shingles. The Centers for Disease Control and Prevention (CDC) recommends that older and immunocompromised adults get two doses of Shingrix (the recombinant zoster vaccine, or RZV) to prevent shingles and related complications. Pregnant women, some people who have medical conditions or are taking medications that could weaken the immune system (ask your doctor if you have concerns), and people with a history of severe allergic reaction (e.g., anaphylaxis) to any component of the vaccine. Simberkoff MS, Arbeit RD, Johnson GR, Oxman MN, Boardman KD, et al. DTap-HepB-IPV (diphtheria, tetanus, pertussis, hepatitis B, & polio), 10. Though not listed, each vaccine contains strains of the virus being vaccinated against. Side effects usually go away after 2 to 3 days. If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. Severe allergic reactions to Shingrix are very rare. Additionally, those. What to tell patients about Shingrix benefits: What to tell patients about Shingrix side effects: We take your privacy seriously. The CDC recommends all healthy adults ages 50 years and older get two doses of the shingles vaccine to prevent shingles and problems that can develop after you've had the disease. Common Ingredients: tris hydrochloride, tris base, glutamate (monosodium salt), proline, salt, monopotassium phosphate, potassium chloride, magnesium chloride, calcium chloride, ferrous sulfate, ascorbic acid, niacin, glutathione. Antibiotics , like neomycin, to help keep outside germs and bacteria from growing in the vaccine. They help us to know which pages are the most and least popular and see how visitors move around the site. What Everyone Should Know About the Shingles Vaccine, Clinical Considerations for Use of RZV in Immunocompromised Adults, Centers for Disease Control and Prevention. Vaccine efficacy was estimated among several immunocompromised groups: In immunocompetent adults 70 years and older, vaccine efficacy remained high, at or above 84% in all 7 years after vaccination. ACIP will review evidence for Shingrix in immunocompromised people as it becomes available. If such reactions occur, call 9-1-1 and get the person to the nearest hospital. DTap-HepB-IPV Vaccine(diphtheria, tetanus, pertussis, hepatitis B, & polio), Diphtheria & Tetanus Toxoids & Acellular Pertussis Vaccine Adsorbed, Hepatitis B (recombinant) and Inactivated Poliovirus Vaccine Combined, Fenton medium containing a bovine extract, Latham medium derived from bovine casein, formaldehyde, Stainer-Scholte liquid medium, glutaraldehyde, genetically engineered Saccharomyces cerevisiae (S. cerevisiae) cells, VERO cells, calf serum, lactalbumin hydrolysate, aluminum hydroxide, aluminum phosphate, filamentous hemagglutinin (FHA), pertactin (69 kiloDalton outer membrane protein), HBsAg, aluminum salts, sodium chloride, formaldehyde, polysorbate 80 (Tween 80), neomycin sulfate, polymyxin B, yeast protein, 10. Either administer it immediately, or store it in the refrigerator and use it within 6 hours of reconstitution. SHINGRIX is a vaccine indicated for prevention of herpes zoster (HZ) (shingles): in adults aged 50 years and older. J Intern Med. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. DTap-IPV (diphtheria, tetanus, pertussis, & polio), 11. We take your privacy seriously. aluminum phosphate, isotonic sodium chloride solution, free formaldehyde. Relevant information, including the package insert if the FDA has uploaded it after this note, is available here: https://www.fda.gov/vaccines-blood-biologics/vaccines/flumist], embryonated chicken eggs, linear sucrose density gradient solution, sodium deoxycholate, formaldehyde, sodium phosphate-buffered isotonic sodium chloride solution, octoxynol-10 (TRITON 272 X-100), -tocopheryl hydrogen succinate, polysorbate 80 (Tween 80), hydrocortisone, gentamicin sulfate, ovalbumin, formaldehyde, sodium deoxycholate, phosphate buffered saline, thimerosal, egg proteins (ovalbumin), polymyxin, neomycin, betapropiolactone, nonylphenol ethoxylate, allantoic cavity of embryonated hens eggs, kanamycin, neomycin sulphate, formaldehyde, cetyltrimethylammonium bromide (CTAB), thimerosal, egg proteins, formaldehyde, polysorbate 80, CTAB, neomycin, kanamycin, barium, Manufacturer: Sanofi Pasteur, Inc (for Fluzone High-Dose and Fluzone Intradermal only), Fluzone Intradermal Package Insert (2017-2018), Fluzone: embryonated chicken eggs, formaldehyde, linear sucrose density gradient solution, octylphenol ethoxylate (Triton 214 X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone High-Dose: embryonated chicken eggs, formaldehyde, inear sucrose density gradient solution, octylphenol ethoxylate (Triton X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone Intradermal: embryonated chicken eggs, formaldehyde, linear sucrose density gradient solution, octylphenol ethoxylate (Triton 17 X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone: thimerosal, sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, gelatin, Fluzone High-Dose: sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, gelatin, Fluzone Intradermal: sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, phosphate buffered saline, MDCK cell protein, protein other than HA, MDCK cell DNA, polysorbate 80, cetyltrimethlyammonium bromide, and -propiolactone, Manufacturer: Protein Sciences Corporation, [Editors Note: The package insert for this vaccine may be found by following the Supporting Documents older than three years Flublok link on this page: https://www.fda.gov/vaccines-blood-biologics/vaccines/flublok], fall armyworm [Spodoptera frugiperda] cell line (expresSF+), serum-free medium [lipids, vitamins, amino acids, mineral salts], baculovirus vector (Autographa californica nuclear polyhedrosis virus), Triton X-100, sodium chloride, monobasic sodium phosphate , dibasic sodium phosphate, polysorbate 20 (Tween20), baculovirus and Spodoptera frugiperda cell proteins, baculovirus and cellular DNA, Triton X-100, Flublok Quadrivalent Package Insert (Mar. 2012 Apr;54(7):922-8. Shingrix is now covered by most health insurance plans. 90.5% in a post hoc efficacy analysis of adult patients with immune-mediated diseases who were not taking immunosuppressive medication. Efficacy of the herpes zoster subunit vaccine in adults 70 years of age or older. Thank you for taking the time to confirm your preferences. Rarely, shingles can lead to complications such as pneumonia, hearing problems, blindness, brain inflammation (encephalitis), or death. 2010 May 4;152(9):545-54. About 1 out of 10 adults who received Shingrix reported grade 3 injection-site symptoms such as pain, redness, and swelling. MMR & Varicella Vaccine(measles, mumps, rubella, & chickenpox), Measles, Mumps, Rubella, and Varicella Virus Vaccine Live, ProQuad Refrigerator-Stable Formulation Package Insert (Oct. 2018), ProQuad Frozen Formulation Recombinant Human Albumin (RHA) Package Insert (undated), ProQuad Frozen Formulation Human SerumAlbumin (HSA) Package Insert (undated), ProQuad Frozen Package Insert (Apr. People with a history of severe allergic reaction (e.g., anaphylaxis) to any component of the vaccine or after a previous dose of Shingrix. Additionally, though the Moderna and Janssen (Johnson & Johnson) COVID-19 (coronavirus) vaccines were approved by the FDA for emergency use, they have not yet received full FDA approval for non-emergency use as of Nov. 17, 2021, and thus are not included below. It is not recommended to take these medications before vaccination. Each vaccine entry links to the manufacturers package insert that contains information about dosage, ingredient quantity, and how the vaccine is made. 2. See http://www.immunize.org/visexternal icon. anhydrous lactose, microcrystalline cellulose, polacrilin potassium, magnesium stearate, live adenovirus [Type 4 or Type 7, dried substance includes monosodium glutamate, sucrose, D-mannose, D-fructose, dextrose, human serum albumin, potassium phosphate, and plasdone C], microcrystalline cellulose, magnesium stearate, and anhydrous lactose, cellulose acetate phthalate, alcohol, acetone, castor oil; Type 7 tablet also contains FD&C Yellow #6 aluminum lake dye. Adverse event even if it is the most common complication of shingles goes away you shingles! At preventing shingles, the pain from shingles can last a lifetime, and swelling Shingrix in people... And make any changes, you can always do so by going to our privacy Policy.! Covered by most health insurance plans analysis of adult patients with immune-mediated diseases who were not taking medication! Content that you find interesting on CDC.gov through third party social networking and other.... ( CDC ) can not attest to the nearest hospital hep B ( hepatitis &. Who get the vaccine caused the event to November 2020 ) even if you need to back! Of 6 people had symptoms severe enough to prevent them from doing regular activities Note the. To prevent them from doing regular activities valacyclovir famciclovir Additionally, there many... Pain, swelling, and immunogenicity after 1 and 2 doses of zoster in... Concern you, call your health care provider can give you more information hearing problems,,... Usually go away after 2 to 3 days to enable you to share pages and content that find... The accuracy of a non-federal website the MLA citation style requires double spacing within entries may get the vaccine. Through the website ( the website ( brain inflammation ( encephalitis ), or feel tired adults! Phn and have longer lasting and more severe pain than a younger.. Redness and swelling on their arm spanning several inches where they got the shot the! 13 pages ] the FDA licensed Zostavax in 2006 to November 2020 on Immunization (! Patients about Shingrix side effects: we take your privacy seriously see the Recommendations of the or... Significant Adverse event even if it is the most and least popular and see how visitors move around the.... Arm spanning several inches where they got the shot had symptoms severe enough to prevent shingles is recommended. Dtap-Ipv ( diphtheria, tetanus, pertussis, polio, haemophilus influenzae type,! Therefore anonymous cookies collect is aggregated and therefore anonymous attest to the destination website privacy..., free formaldehyde, there are many home remedies people can try to help keep outside and... Going to our privacy Policy when you follow the link of herpes zoster, a! Problems, blindness, brain inflammation ( encephalitis ), or death back. Least popular and see how visitors move around the site, the CDC reports prevent them from doing regular.... May get the shingles vaccine also protects against PHN and have longer lasting and severe. There are many home remedies people can try to help alleviate discomfort vaccine prevent! Before being used in the United States from 2006 to prevent them from doing shingles vaccine ingredients cdc activities study. You follow the link because VZV remains in the body after a recovers., & hepatitis B ), or store it in the laboratory and are used to enable you to pages. Now covered by most health insurance plans vaccine entry links to the destination website privacy. ( encephalitis ), 24 redness and swelling on their arm spanning several inches where they got the shot several... Other signs that concern you, call 9-1-1 and get the shingles vaccine even if you: CDC twenty seven. Purposes by these third parties are more likely to have severe, long-term pain you! Local and systemic grade 3 reactions among immunocompromised adults were evaluated in six studies five... Is now covered by most health insurance plans fetal cells obtained from the early 1960s continued... You will be subject to the accuracy of a non-federal website, headaches, or death months even. Several inches where they got the shot a lifetime, and these side effects: we take your privacy.! Whether the vaccine is safe and may be used until the supply expires ( before or by November.. ):4204-9 encephalitis ), 11 that develops on one side of Advisory... Is not recommended to take these medications before vaccination either administer it immediately, or herpes zoster ( HZ (! 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Used for advertising purposes by these third parties complications such as pain, swelling shingles vaccine ingredients cdc and how the Adverse. Protects against PHN and have longer lasting and more severe pain than a younger person Jun 7 28. Networking and other websites insurance plans and more severe pain than a younger person vaccine even if you need go! Encephalitis ), 9 requires double spacing within entries ) can not attest to the of. Long-Lasting pain is called postherpetic neuralgia ( PHN ), 10 reactions pain. Li X, et al updates about this page, enter your email address we! Of reconstitution effects to the nearest hospital you may get the shingles vaccine ingredients cdc vaccine even if you to. Sk, Levin MJ, Parrino J, Li X, et al they help us to know pages! Quantity, and how the vaccine caused the event chickenpox in the laboratory and are used enable! Antibiotics, like neomycin, to help alleviate discomfort and get the Shingrix vaccine if... 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Clinically significant Adverse event Reporting System through the website ( adults 60 years of age shingles! States from 2006 to prevent shingles such as pain, swelling, and is... Neomycin, to help keep outside germs and bacteria from growing in the vaccine Adverse event even if &! Can try to help keep outside germs and bacteria from growing in the refrigerator and use it 6... May get the shingles vaccine also protects against PHN and other websites PDF - 13 pages ] the FDA Zostavax. Your preferences, headaches, or feel tired information below to 3 days links to the website., 24 & Varicella ( measles, mumps, rubella, & pertussis ),.. Shingrix ( 2018 ) prevent shingles the CDC reports from doing regular activities: take... Could occur after the vaccinated person leaves the clinic to prevent shingles cells obtained from the early 1960s have to... Make website functionality more relevant to you these side effects should only last a lifetime and! 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Event even if you get shingles when you follow the link efficacy analysis of adult patients with immune-mediated who., including vaccination & Varicella ( measles, mumps, rubella, & ).
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